Remote opportunity at
Vir Biotechnology, Inc.Senior Director, Head of Clinical Pharmacology
Vir Biotechnology, Inc. is seeking a Senior Director, Head of Clinical Pharmacology to lead departmental technical and operational functions. The organization focuses on creating medicines for…
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About This Role
Vir Biotechnology, Inc. is seeking a Senior Director, Head of Clinical Pharmacology to lead departmental technical and operational functions. The organization focuses on creating medicines for serious infectious diseases and cancer through its clinical-stage pipeline, including chronic hepatitis delta programs, PRO-XTEN dual-masked T-cell engagers, and various preclinical programs. Reporting to the VP of Translational Development, this remote, full-time leadership position requires managing a team, collaborating with internal and external cross-functional…
Job Description
Vir Biotechnology, Inc. is seeking a Senior Director, Head of Clinical Pharmacology to lead departmental technical and operational functions. The organization focuses on creating medicines for serious infectious diseases and cancer through its clinical-stage pipeline, including chronic hepatitis delta programs, PRO-XTEN dual-masked T-cell engagers, and various preclinical programs. Reporting to the VP of Translational Development, this remote, full-time leadership position requires managing a team, collaborating with internal and external cross-functional groups, and providing strategic direction for drug development programs spanning preclinical phases through market authorization.
The ideal candidate will provide hands-on leadership, oversee translational pharmacokinetic and pharmacodynamic operations, and design clinical pharmacology strategies that guide regulatory and developmental milestones. The successful applicant will direct modeling and simulation initiatives, contribute to regulatory document preparation, and cultivate partnerships with external vendors. This role suits an experienced professional who possesses deep technical knowledge in pharmacokinetics and drug development, combined with a proven background in building and mentoring high-performing teams.
Responsibilities
- Oversee clinical pharmacology and translational pharmacokinetic and pharmacodynamic operations across all development phases for oncology and infectious disease programs
- Act as the technical expert for clinical pharmacology on cross-functional project teams to deliver strategic input
- Design fit-for-purpose clinical pharmacology strategies to inform regulatory and development decisions from pre-IND to market authorization
- Select and execute modeling and simulation approaches including pharmacokinetics, pharmacodynamics, population pharmacokinetics, and exposure-response to guide dose selection and optimization
- Author and supply technical input for regulatory submissions, protocols, investigator brochures, briefing packages, and regulatory question responses
- Collaborate across cross-functional teams covering clinical research, clinical operations, biomarkers, bioanalytical, biometrics, chemistry manufacturing and controls, research, and regulatory
- Establish and oversee collaborations with external vendors and partners
- Create and manage departmental budgets while optimizing resource allocation across multiple programs
- Manage, recruit, mentor, and build the Clinical Pharmacology and Translational team
Requirements
- PhD, PharmD, or MD with relevant training in clinical pharmacology, pharmacokinetics, pharmaceutics, or a related field
- 13 or more years of industry experience in clinical pharmacology, drug metabolism and pharmacokinetics, or related fields
- Mastery of nonclinical and clinical pharmacokinetic concepts, methodologies, and multidisciplinary drug development requirements
- Extensive experience directing translational and clinical pharmacology work from candidate selection through market authorization
- Strong understanding of regulatory requirements with experience contributing to regulatory submissions and engagements
- Working knowledge of bioanalytical techniques applied to the clinical development of biologics and small molecules
- Direct experience working with biologics, encompassing monoclonal antibodies and bispecifics
- Proficiency in utilizing standard pharmacokinetics analysis and graphing software
- Demonstrated ability to develop and manage teams
- Authorization to work for any U.S. employer without the need for visa sponsorship
Qualifications
- Experience in oncology indications is strongly preferred
Core Skills
Benefits
- Expected salary range between $235,500 and $329,500 per year
- Compensation package including salary, bonus, and equity
- Health and welfare benefit plans
- Non-accrual paid time off
- Company shutdown for holidays
- Commuter benefits
- 401K match
- Daily lunch provided in the office
Frequently Asked Questions
Answers are based only on the employer’s listing; where it doesn’t say, neither do we.
What is the location and remote status of this role?
This position is listed as remote.
What is the expected salary range for the Senior Director, Head of Clinical Pharmacology?
The expected salary range is $235,500 to $329,500 per year, with actual pay determined by experience, qualifications, geographic location, and other job-related factors.
Does the company offer visa sponsorship for this position?
No, applicants must currently be authorized to work for any employer in the U.S., and the company is unable to sponsor or take over sponsorship of an employment visa at this time.
Who does this position report to?
This role reports to the Vice President of Translational Development.
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