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Axsome Therapeutics, Inc.

Senior Manager, Finance

Axsome Therapeutics, Inc. is searching for a Senior Manager, Finance to join its team. The organization operates as a biopharmaceutical company focusing on central nervous system…

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Role Snapshot

Hiring Now
Work arrangement
Remote
Where applicants may be
Applicants in United States only
Salary
USD 130,000 - 150,000/yr
Apply by
Not specified
Employment type
Full-time
Experience
Not specified
Added to Jobsiz2h agoEmployer posted Oct 15, 2026
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Applications0
Apply BeforeNo deadline

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About This Role

Axsome Therapeutics, Inc. is searching for a Senior Manager, Finance to join its team. The organization operates as a biopharmaceutical company focusing on central nervous system conditions, creating neuroscience products designed to improve patient outcomes. This hybrid position requires working on site at the company headquarters in New York City on Mondays, Tuesdays, and Thursdays. Fully remote candidates cannot be considered for this opening. The person in this role will…

Job Description

Axsome Therapeutics, Inc. is searching for a Senior Manager, Finance to join its team. The organization operates as a biopharmaceutical company focusing on central nervous system conditions, creating neuroscience products designed to improve patient outcomes. This hybrid position requires working on site at the company headquarters in New York City on Mondays, Tuesdays, and Thursdays. Fully remote candidates cannot be considered for this opening.

The person in this role will guide external financial reporting cycles, oversee technical accounting research, and manage internal controls in compliance with SOX 404. Duties include preparing SEC filings such as Forms 10-Q and 10-K, drafting accounting policies, and serving as a liaison across legal, investor relations, and auditing teams. The position reports directly to the Senior Director, Finance.

Ideal candidates possess progressive accounting experience combining public accounting with technical accounting or SEC reporting backgrounds. Strong collaboration abilities, technical research skills, and familiarity with U.S. GAAP are essential for managing multiple deadlines in this fast-paced corporate setting.

Responsibilities

  • Prepare external financial statements, footnotes, statement of cash flows, and Management's Discussion and Analysis for Forms 10-Q and 10-K
  • Perform XBRL reviews and assemble supporting schedules for periodic SEC filings
  • Research and write technical accounting memoranda addressing non-routine transactions like share-based compensation, business combinations, debt instruments, and licensing arrangements
  • Track new SEC rulemaking and accounting pronouncements to lead implementation and documentation
  • Support design, improvement, and testing of business process internal controls under SOX 404
  • Draft new accounting policies and update existing ones periodically
  • Partner with internal teams, legal, investor relations, and external audit providers

Requirements

  • Certified Public Accountant license
  • At least 7 years of progressive accounting experience
  • Working knowledge of SEC reporting requirements and U.S. GAAP
  • Public company experience with SOX 404 compliance including control design and testing
  • Ability to work on site in New York City on Mondays, Tuesdays, and Thursdays

Qualifications

  • Bachelor's or Master's degree in Finance, Accounting, or a related field
  • Background combining public accounting with SEC reporting or technical accounting
  • Familiarity with financial reporting software such as Workiva or DFIN Active Disclosure
  • Experience within the life sciences or biopharmaceutical sector
  • Proficiency with research applications like FASB codifications, Checkpoint, or Intelligize
  • Experience using financial close and ERP systems including Microsoft Dynamics 365 Business Central

Core Skills

Benefits

  • Annual bonus
  • Significant equity
  • Generous benefits package

Frequently Asked Questions

Answers are based only on the employer’s listing; where it doesn’t say, neither do we.

What is the location and work schedule for this role?

This position is based at the employer headquarters in New York City and requires working on site every Monday, Tuesday, and Thursday. Fully remote arrangements are not available.

What salary is offered for the Senior Manager, Finance position?

The expected salary range spans from $130,000 to $150,000 per year, with final compensation depending on qualifications, experience, internal equity, and location.

What are the primary educational and certification requirements?

Applicants must hold a CPA license alongside a Bachelor's or Master's degree in Accounting, Finance, or a related discipline.

Sample Interview Questions

AI-generated questions tailored to this specific role — a preview of the full practice set.

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Posted by Axsome Therapeutics, Inc.

Source: Remote First Jobs — HR

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Posted by employer: Oct 15, 2026

Added to Jobsiz: Oct 16, 2026

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Axsome Therapeutics, Inc.

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