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Freenome

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Freenome

Senior Software Engineer, Site Reliability

Freenome is seeking a Senior Software Engineer, Site Reliability to join its newly established Site Reliability Engineering team as a founding member. In this remote, full-time…

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Role Snapshot

Hiring Now
Work arrangement
Remote
Where applicants may be
Not specified
Salary
USD 131,325 - 189,525/yr
Apply by
Not specified
Employment type
Full-time
Experience
Not specified
Added to Jobsiz7h agoEmployer posted Oct 31, 2026
Listing Views2
Applications0
Apply BeforeNo deadline

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About This Role

Freenome is seeking a Senior Software Engineer, Site Reliability to join its newly established Site Reliability Engineering team as a founding member. In this remote, full-time role, the engineer will help transition the company from research to commercial operations by building reliable systems for regulated, cloud-based production environments and clinical lab workloads. The position reports to the Director, Cloud Infrastructure and focuses on observability, incident management, reliability, and regulatory compliance.…

Job Description

Freenome is seeking a Senior Software Engineer, Site Reliability to join its newly established Site Reliability Engineering team as a founding member. In this remote, full-time role, the engineer will help transition the company from research to commercial operations by building reliable systems for regulated, cloud-based production environments and clinical lab workloads. The position reports to the Director, Cloud Infrastructure and focuses on observability, incident management, reliability, and regulatory compliance.

This opportunity is ideal for professionals with substantial experience running cloud production workloads who want to establish an SRE practice from the beginning. Key responsibilities include creating observability practices, partnering on service-level objectives, automating operational tasks, participating in on-call rotations, and contributing to change-management processes aligned with FDA and compliance requirements.

Responsibilities

  • Design, implement, and operate observability practices including metrics, traces, dashboards, logs, and alerts for production systems
  • Collaborate with product, engineering, and lab teams to build and maintain incident response playbooks and escalation procedures
  • Partner with engineering groups to define service-level indicators, objectives, and error budgets
  • Participate in the on-call rotation for production systems with a focus on automation and self-healing
  • Contribute to production deployment and change-management processes meeting FDA and compliance standards
  • Automate operational tasks to minimize manual intervention
  • Build and deploy team-owned infrastructure and subsystems using Infrastructure as Code
  • Participate in cross-functional incident reviews, postmortems, and tabletop or disaster recovery exercises
  • Provide mentorship to peers regarding observability, incident management, and operational best practices

Requirements

  • 5 or more years of experience in software engineering, Infrastructure, DevOps, or SRE roles, with a preference for Python or Go
  • Experience deploying cloud infrastructure via automation tools such as Terraform, Pulumi, or Bicep/ARM
  • Hands-on background operating production workloads within cloud environments
  • Familiarity with Kubernetes platforms including AKS, GKE, or EKS
  • Strong troubleshooting and root-cause analysis capabilities in distributed systems
  • Practical experience with observability platforms like DataDog, Prometheus/Grafana, or OpenTelemetry
  • Ability to independently drive reliability improvements and own technical outcomes
  • Solid understanding of cloud infrastructure, networking architectures, and automation

Qualifications

  • Bachelor's degree in Computer Science, Engineering, or equivalent experience
  • Experience supporting regulated environments such as healthcare, biotech, or finance
  • Familiarity with compliance-driven change management and release processes including FDA and HIPAA
  • Experience utilizing incident management platforms like Incident.io, ServiceNow, Opsgenie, or PagerDuty
  • Knowledge of CI/CD deployment strategies and change automation
  • Experience working with both GCP and Azure cloud platforms

Core Skills

Benefits

  • Base salary target range between USD 131,325 and USD 189,525 per year
  • Eligibility to receive equity and cash bonuses
  • Full range of medical, financial, and additional benefits

Frequently Asked Questions

Answers are based only on the employer’s listing; where it doesn’t say, neither do we.

What is the remote status of this role?

This position is fully remote.

What is the salary range for this position?

The target base salary range is USD 131,325 to 189,525 per year, with additional eligibility for equity and cash bonuses.

What level of experience is required?

Applicants must have a bachelor's degree in Computer Science or Engineering (or equivalent experience) alongside at least 5 years of professional experience in software engineering, DevOps, SRE, or infrastructure roles.

How do I apply for this job?

The posting does not specify an application method other than directing applicants to check the career page at freenome.com/job-openings/ for further company information.

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Posted by Freenome

Source: Remote First Jobs — Software Development

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Posted by employer: Oct 31, 2026

Added to Jobsiz: Nov 5, 2026

The description was written by Jobsiz from the employer’s listing. Always check the original listing before applying.

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