
Remote opportunity at
NateraAssociate Director / Director of Product Management, Signatera Hematologic Oncology (Heme)
Natera is a worldwide leader in cell-free DNA testing, specializing in oncology, women's health, and organ health with the goal of improving disease management and enabling…
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About This Role
Natera is a worldwide leader in cell-free DNA testing, specializing in oncology, women's health, and organ health with the goal of improving disease management and enabling earlier interventions. The company is seeking an Associate Director / Director of Product Management, Signatera Hematologic Oncology (Heme) to spearhead the product strategy and roadmap for Signatera in hematologic malignancies, beginning with multiple myeloma and lymphomas. This position involves collaborating across departments including R&D,…
Job Description
Natera is a worldwide leader in cell-free DNA testing, specializing in oncology, women's health, and organ health with the goal of improving disease management and enabling earlier interventions. The company is seeking an Associate Director / Director of Product Management, Signatera Hematologic Oncology (Heme) to spearhead the product strategy and roadmap for Signatera in hematologic malignancies, beginning with multiple myeloma and lymphomas. This position involves collaborating across departments including R&D, Lab Operations, Software Engineering, Medical Affairs, Marketing, Business Development, and Regulatory.
The role encompasses leading laboratory developed test (LDT) market entry, clinical trial product support, evidence generation, analytics, and product guidance for whole genome sequencing technologies. The ideal candidate will possess a background in product management or marketing within diagnostics, biotech, or pharmaceutical settings, along with expertise in oncology molecular testing and next-generation sequencing. The position requires availability during Pacific time hours and involves thirty to forty percent travel for advisory boards, congresses, and customer meetings.
Responsibilities
- Develop and execute the product roadmap for Signatera in hematologic malignancies, starting with multiple myeloma and lymphomas.
- Lead market entry planning for Signatera as a laboratory developed test, addressing clinical validation, regulatory requirements, and launch readiness.
- Define product requirements for blood-based malignancies in coordination with R&D, Lab Operations, and Software Engineering.
- Provide product support for clinical trials utilizing Signatera in heme, including investigational use only studies and the pathway to regulated use.
- Build product performance metrics and dashboards to analyze test volume, adoption, ordering patterns, turnaround time, and retention.
- Partner with Medical Affairs and Clinical teams on evidence generation strategies, study designs, and publications.
- Guide product development for Signatera Genome in heme, incorporating whole genome sequencing technology and variant types.
- Conduct Voice of Customer interviews, market research, and competitive intelligence with key opinion leaders and medical congresses.
- Collaborate with Marketing on positioning, pricing, launch plans, and business cases for executive leadership presentation.
Requirements
- Experience in product management, product marketing, or market analytics at a diagnostics, biotech, or pharmaceutical company.
- Working knowledge of oncology molecular testing, next-generation sequencing, biomarkers, and bioinformatic workflows.
- Experience in investigational use only and regulated in vitro diagnostic environments.
- Experience bringing a molecular test to market as a laboratory developed test, including clinical validation and laboratory requirements.
- Experience designing or supporting clinical evidence generation such as validation, retrospective, or prospective studies.
- Availability during Pacific time hours.
Qualifications
- Bachelor's degree in life sciences, statistics, engineering, or a related field; advanced degree in MS, PhD, or MBA preferred.
- 5+ years (7+ preferred) of experience in product management, product marketing, or market analytics.
- Hematologic oncology experience strongly preferred, especially in multiple myeloma and lymphoma.
- Molecular residual disease experience preferred.
- Data analysis experience using SQL, Snowflake, or similar tools preferred.
- Familiarity with high complexity molecular laboratories and cfDNA or plasma workflows.
- In-depth knowledge of whole genome sequencing and variant types including structural, single nucleotide, and phased variants.
- Prior key opinion leader engagement and external customer-facing experience.
Core Skills
Benefits
- Comprehensive medical, dental, vision, life, and disability plans for eligible employees and dependents.
- Free testing for employees and immediate families alongside fertility care benefits.
- Pregnancy and baby bonding leave.
- 401k benefits.
- Commuter benefits.
- Employee referral program.
Frequently Asked Questions
Answers are based only on the employer’s listing; where it doesn’t say, neither do we.
What is the employment type for this position?
This is a full-time position.
Is travel required for this role?
Yes, travel is required at 30-40% for attending advisory boards, congresses, and customer meetings.
What is the salary for this job?
The pay range for remote USA is $180,300 to $230,900 USD, with actual compensation based on factors such as skills, experience, and location.
What are the location and working hour expectations?
The position can be based anywhere in the United States, but availability during Pacific time hours is required, and site-based presence in San Carlos, CA, Boulder, CO, or Austin, TX is preferred.
Sample Interview Questions
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