Remote opportunity at
NateraProduct Manager, Lab Execution Oncology (Signatera)
Natera is seeking a Product Manager to lead software development for the Signatera Plasma high-throughput laboratory, focusing on oncology genomics workflows from sample intake through sequencing.…
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About This Role
Natera is seeking a Product Manager to lead software development for the Signatera Plasma high-throughput laboratory, focusing on oncology genomics workflows from sample intake through sequencing. In this position, you will collaborate closely with engineering, research and development, lab operations, and automation teams to translate laboratory needs into functional software features. Your daily work will directly impact laboratory speed, reliability, and precision while helping patients and families obtain critical genetic…
Job Description
Natera is seeking a Product Manager to lead software development for the Signatera Plasma high-throughput laboratory, focusing on oncology genomics workflows from sample intake through sequencing. In this position, you will collaborate closely with engineering, research and development, lab operations, and automation teams to translate laboratory needs into functional software features. Your daily work will directly impact laboratory speed, reliability, and precision while helping patients and families obtain critical genetic health insights. The role involves managing product features, writing requirements, designing user-centered workflows, and ensuring compliance within a regulated clinical laboratory environment. Natera operates as a global leader in cell-free DNA testing, specializing in oncology, women's health, and organ health diagnostics.
This is a full-time, remote position offering a base salary range of USD 127,500 to 151,500 per year, accompanied by a comprehensive total rewards package including equity, annual bonuses, and health benefits.
Responsibilities
- Manage product features and enhancements for next-generation sequencing lab workflows according to team priorities
- Draft detailed user stories, acceptance criteria, flow diagrams, wireframes, and simple prototypes
- Groom and prioritize product backlogs in partnership with the engineering team
- Identify and resolve operational bottlenecks on the lab floor regarding tracking, inventory, and instrument availability
- Create quality documentation and release notes to support verification and validation activities
- Support new product and panel launches through user acceptance testing, go-live, and hypercare phases
- Track performance indicators including throughput, turnaround times, rework rates, and feature adoption
- Collaborate with quality and regulatory teams to ensure compliance in a regulated clinical setting
- Partner with lab operations, research, automation, and bioinformatics stakeholders to gather user feedback and requirements
Requirements
- Experience in product management, business analysis, or a related software product role within labs, healthcare, or regulated industries
- Proficiency in authoring technical requirements and user stories
- Application of UX design thinking for user-centered workflows
- Capacity to understand complex scientific and genomics processes rapidly
- Analytical capability utilizing data and dashboards for decision-making
- Familiarity with Agile frameworks such as Scrum or Kanban, along with Jira and Confluence
- Demonstrated written, verbal, and organizational communication skills
Qualifications
- Based in the Bay Area around San Carlos, California, or available for 25 to 35 percent travel
- Background working in or alongside a clinical or molecular laboratory
- Familiarity with LIMS, LES, or comparable lab software solutions
- Exposure to germline, carrier screening, or hereditary testing workflows
- Prior work with lab automation, integrated workcells, or instrument integration
- Proficiency in SQL
- Experience applying artificial intelligence tools to enhance efficiency
Core Skills
Benefits
- Annual performance incentive bonus
- Long-term equity awards
- Comprehensive health benefits including medical, dental, and vision coverage
- 401(k) plan with company match
- Generous paid time off and company holidays
- Additional wellness and work-life benefits
Frequently Asked Questions
Answers are based only on the employer’s listing; where it doesn’t say, neither do we.
Is this position remote?
Yes, the posting explicitly lists the remote status as remote.
What is the salary range for this role?
The base salary range is between USD 127,500 and 151,500 per year, with final compensation depending on experience, qualifications, and internal equity.
What type of employment is this?
This is a full-time employment opportunity.
Are there travel or location preferences for nice-to-have qualifications?
Preferred candidates may be based in the Bay Area in San Carlos, California, or show a willingness to travel approximately 25 to 35 percent.
Sample Interview Questions
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